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Contact

daveritt@twu.edu
940-898-2708
SRC 204C

Biography

Dr. Dayna Averitt earned her Bachelors degree from the University of Texas at Austin in 2001 and her PhD in Neuroscience in 2008 from Georgia State University. Under the mentorship of Dr. Anne Murphy, Dr. Averitt studied the neural correlates of sex differences in morphine analgesia. She then completed postdoctoral training at the University of Texas Health Science Center in San Antonio in 2011 under the mentorship of Dr. Ken Hargreaves studying serotonergic modulation of the TRPV1 population of trigeminal nociceptors. Dr. Averitt worked as a Principle Investigator at the United States Army Institute of Surgical Research at the San Antonio Military Medical Center for two years where she managed research projects on preemptive analgesia for nerve injury and peripheral analgesia for burn pain. In 2014, Dr. Averitt joined the faculty at the ²ÝÝ®´«Ã½¹ÙÍøÏÂÔØ as an Assistant Professor. Dr. Averitt has published 20 peer-reviewed research articles under funding from the Department of Defense and the National Institutes of Health. The Averitt Neurosensory Research Lab is focused on studying sex differences in pain and analgesia.

Education

Ph.D., Neuroscience, Georgia State University, Atlanta, GA
M.S., Clinical Investigation, University of Texas Health Science Center at San Antonio, San Antonio, TX
M.S., Biology, Georgia State University, Atlanta, GA
B.A., Psychology, University of Texas at Austin, Austin, TX

Research Interests

Neuroscience; Neuroanatomy; Sensory Systems; Pain Mechanisms; Pain Management; Opioid and Non-opioid Analgesia; Inflammation; Sex Differences; Trigeminal System; Animal Models

Latest Articles

Antioxidants (2022)
Paramita Basu, Dayna L Averitt, Camelia M. Maier, Arpita Basu

Journal of Chemical Neuroanatomy (2022)
Daisy J Cantu, Sukhbir Kaur, Anne Z Murphy, Dayna L Averitt

PAIN (2022)
Sukhbir Kaur, Taylor M Hickman, Angela Lopez-Ramirez, Hanna McDonald, Omar Darwish

Molecular Pain (2022)
Rebecca H Hornung, Namrata G.R. Raut, Daisy J Cantu, Lauren M Lockhart, Dayna L Averitt

Texas Journal of Microscopy (2021)
Sukhbir Kaur, Angela Lopez-Ramirez, Taylor M Hickman, Michael Paul Hunter, Dayna L Averitt

Neurobiology of Pain (2021)
Sukhbir Kaur, Hanna McDonald, Sirima Tongkhuya, Cierra M.C. Lopez, Sushmitha Ananth

Frontiers in Integrative Neuroscience (2020)
Rebecca S. Hornung, William L. Benton, Sirima A. Tongkhuya, Lynda Uphouse, Phillip Kramer

Oxidative Medicine and Cellular Longevity (2019)
Paramita Basu, Rebecca S. Hornung, Camelia M. Maier

Frontiers in Pharmacology (2019)
Paramita L Basu, Sirima A Tongkhuya, Taylor L Harris, Angela R Riley, Camelia Maier

Neuropsychopharmacology (2019)
Dayna L Averitt, Lori N Eidson, Hillary H Doyle, Anne Z Murphy

Neuroscience (2018)
Sukhbir Kaur, William L Benton, Sirima A Tongkhuya, Cierra C.M.C Lopez, Dayna L Averitt

Pain Medicine (2017)
Margaux M Salas, John L Clifford, Jessica R Hayden, Michael J Iadarola, Dayna L Averitt

Burns (2015)
Jennifer E Nyland, Samuel A McLean, Dayna L Averitt

BMC Anesthesiology (2015)
John L Clifford, Alberto Mares, Jacob J. Hansen, Dayna L. Averitt

Chapters

Euphorbia bicolor (Euphorbiaceae) Latex Phytochemicals and Applications to Analgesia
in The Neuroscience of Anesthetics and Analgesics | Elsevier Inc. (2021)
Paramita Basu, Dayna L Averitt, Camelia M. Maier

Role of Sex Hormones on Pain
in Oxford Encyclopedia of Neuroendocrine and Autonomic Systems | Oxford University Press (2019)
Dayna L Averitt, Rebecca S Hornung, Anne Z Murphy

Current Projects

Sex Differences in Pain and Analgesia: Many chronic pain conditions occur predominantly in women and women are less sensitive to opioid-based pain medications. We have three major projects attempting to address this issue:
Sex Differences in Serotonergic Modulation of Trigeminal Pain. Pain conditions are exacerbated by hormone fluctuations, yet the effect of hormones on pain mechanisms remains controversial. The peripheral serotonin system and its activity at nerve endings that express an ion channel called TRPV1 represents one pain mechanism that may be modulated by hormones. We have a grant from the National Institute on Dental and Craniofacial Research to elucidate how hormones modulate the ‘pain-producing’ effects of 5HT on the TRPV1 population of sensory neurons.
Identification of Novel Non-Opioid Analgesics. In collaboration with Dr. Camelia Maier (²ÝÝ®´«Ã½¹ÙÍøÏÂÔØ) and the Army, we are examining the analgesic effects of novel plant phytochemicals.
Sex Differences in the Neuroanatomy of Descending Pain Inhibition. In collaboration with Dr. Anne Murphy (Georgia State University), we are identifying novel neural pathways underlying sexually dimorphic descending pain inhibition in females.

Externally Funded Projects

NRSA F31: Sex Differences in Stress-Exacerbated Orofacial Pain in a Rat Model of Temporomandibular Joint Disorder Year 1 of 2
GOV-National Institute of Dental and Craniofacial Research (NIDCR) | $34,635.00 | 2022
Role: Co-Principal Investigator

Diversity Supplement - Daisy Cantu Year 2 of 2
GOV-National Institute of Dental and Craniofacial Research (NIDCR) | $48,072.00 | 2022
Role: Principal Investigator

Sex Differences in Serotonergic Modulation of Trigeminal Pain Year 3 of 3
GOV-National Institute of Dental and Craniofacial Research (NIDCR) | $385,514.00 | 2021
Role: Principal Investigator

Internally Funded Projects

Sex Differences in the Development of Pain in a Translational Model of Temporomandibular Joint Disorder
Research Enhancement Program Grant, ²ÝÝ®´«Ã½¹ÙÍøÏÂÔØ | $10,000.00 | 2022
Research Grant

Effect of Estrogen on the Neuroimmune Crosstalk Between Macrophages and Trigeminal Sensory Neurons
Research Enhancement Program Grant, ²ÝÝ®´«Ã½¹ÙÍøÏÂÔØ | $10,000.00 | 2021
Research Grant

Studies on the Antioxidant Phytochemicals in Euphorbia bicolor (Euphorbiaceae) and their Mechanisms of Action in Reducing Inflammation and Pain
Research Enhancement Program Grant, ²ÝÝ®´«Ã½¹ÙÍøÏÂÔØ | $10,000.00 | 2018
Research Grant

Dual Reagent Injection Module for Biotek Synergy H1 Citation System
Teaching and Research Grant for Equipment and Technology (TARGET) | $8,000.00 | 2018
Research Grant

Patch Clamp Electrophysiology Rig
Teaching and Research Grant for Equipment and Technology (TARGET) | $120,000.00 | 2017
Research Grant

Estrogen Enhances the Pain-evoking Effects of Serotonin
Research Enhancement Program (REP) New Investigator Competition Grant, ²ÝÝ®´«Ã½¹ÙÍøÏÂÔØ | $10,000.00 | 2017
Research Grant

Role of the 5HT2A receptor on Estrous-cycle Dependent Changes in Pain
Research Enhancement Program (REP) New Investigator Competition Grant, ²ÝÝ®´«Ã½¹ÙÍøÏÂÔØ | $10,000.00 | 2016
Research Grant

Effects of Estrous Cycle on Trigeminal Pain
Research Enhancement Program (REP) New Investigator Competition Grant, ²ÝÝ®´«Ã½¹ÙÍøÏÂÔØ | $10,000.00 | 2015
Research Grant

Professional Affiliations

• American Association for Dental Research
• American Pain Society
• International Association for Dental Research
• International Association for the Study of Pain
• Society for Neuroscience
• Texas Pain Research Consortium